PMDD stands for Premenstrual Dysphoric Disorder. It is a rare component of Premenstrual Syndrome. PMDD, which affects about 5% of all menstruating women, is described by the American Psychiatric Association as a pattern of recurrent symptoms of depression and other negative moods that occur during the last week of the menstrual cycle. These PMDD symptoms are so severe that they markedly interfere with daily living. Some of the symptoms are: